The goal of my research program is to translate state-of-the-art scientific findings to clinically relevant strategies for the improvement of outcomes in global pediatric infections. Malaria, pneumonia, and tuberculosis are examples of globally important childhood diseases that are current areas of investigation. My program of research includes basic science disease models, clinical trials in resource-limited settings and social determinants of infectious diseases (e.g., human conflict in the Congo). This work aims to accelerate discovery to impact in terms of patient outcomes, applying principles of infectious disease pathogenesis to identify innovative diagnostic strategies and potential therapeutic targets. This program of research is grounded within a global ethical framework, which sees the world as increasingly interconnected and implicated in the concerns of vulnerable pediatric populations worldwide.