Stephane Bourque

Summary:

My research program focuses primarily on the mechanisms by which developmental stressors alter the growth trajectory of the fetus and neonate, and in turn increase susceptibility to cardiovascular and metabolic diseases in later life. I am particularly interested in perinatal iron deficiency and neonatal sepsis - two prevalent but understudied health complications that can profoundly affect newborn development and in turn life-long health. I also study the maternal and fetal effects of novel therapeutics (e.g. bioactive compounds) in pregnancy. Indeed, while the growing fetus is particularly vulnerable to insults during pregnancy, it follows that it may also be more responsive to therapeutics. Properly instituted, such interventions could be used to mitigate the damage caused by insults such as iron deficiency or sepsis, and thus promote long-term health and resilience in the offspring.